Shannon kane ethnicity test
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Abstract
Background:
We recently developed a multi-ancestry polygenic risk score (PRS) that effectively stratifies prostate cancer risk across populations. In this study, we validated the performance of the PRS in the multi-ancestry Million Veteran Program and additional independent studies.
Methods:
Within each ancestry population, the association of PRS with prostate cancer risk was evaluated separately in each case–control study and then combined in a fixed-effects inverse-variance-weighted meta-analysis. We further assessed the effect modification by age and estimated the age-specific absolute risk of prostate cancer for each ancestry population.
Results:
The PRS was evaluated in 31,925 cases and 490,507 controls, including men from European (22,049 cases, 414,249 controls), African (8794 cases, 55,657 controls), and Hispanic (1082 cases, 20,601 controls) populations. Comparing men in the top decile (90–100% of the PRS) to the average 40–60% PRS category, the prostate canc
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Discovering America's Black DNA
Anne Strainchamps (00:00):
It's To The Best Of Our Knowledge, I'm Anne Strainchamps. Meet Reverend Alex Gee. Like a lot of us, he's interested in his family history.
Alex Gee (00:15):
I've always been interested in genealogy. It's always intrigued me to know where my family name came from. My entire life I've been asked, "Where does Gee komma from?"
Anne Strainchamps (00:30):
So he started digging around.
Alex Gee (00:34):
My great-great-grandfather was born a slave. His name was Henderson. And so about a year ago, I googled his name and through Ancestry.com, inom found out that his father's name was Reuben Joshua Gee.
Anne Strainchamps (00:46):
But here's the kicker: the relatives Alex Gee funnen are vit. And he discovered that he's part white as well.
Alex Gee (00:57):
I funnen a brev from a gentleman named John who basically said, "I just found out that my great-great-grandfather had a Black son. Does anyone know anything about Henders
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It is possible to get a free DNA test whether or not you are able to make it to Back to Our Past. These tests are sponsored by Project Administrators who run specific projects at FTDNA (FamilyTreeDNA). Most of them are members of ISOGG (International Society of Genetic Genealogy).
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